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Upon re-awakening in full, Apocalypse came into conflict with the original X-Men (then organized as the superhero team X-Factor) on repeated occasions. When one of their number, the Angel, lost his wings, Apocalypse granted him an artificial pair in exchange for his servitude; Angel accepted, becoming Apocalypse's Angel of Death, but eventually he rebelled. Later, Apocalypse infected Cyclops's son Nathan with a "techno-organic virus" derived from the alien technology that gave him his powers; as a result, Nathan was sent to the future for a cure, where he became the time-travelling superhero known as Cable.
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